South Carolina Midlands – Hotels, Motels, Inns, Resorts
See also Coastal SC Hotels | Upstate SC Hotels | All SC Hotels | US Hotel Guide
This guide can help you choose a place to stay in central South Carolina – the area between the coastal lowlands and the foothills in the northwest. You can also use it to make secure reservations online with immediate confirmation.
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Choose a Midlands city ...
- Aiken - horse races, golf, Savannah River Site
- Barnwell - Savannah River Site
- Bennettsville
- Bishopville - close to I-20
- Blythewood - north of Columbia - close to I-77
- Camden - horse races
- Cayce - just south of Columbia, near airport
- Cheraw
- Columbia - state capital, University of SC, Ft Jackson, zoo
- Dillon - South of the Border - close to I-95
- Florence - Francis Marion University - I-20 at I-95
- Fort Jackson - Army training center - east Columbia
- Fort Mill - Lake Wylie, Carowinds - just south of Charlotte
- Hampton
- Hartsville - Coker College, Sonoco headquarters
- Irmo - Lake Murray, boating
- Kingstree - SC's barbeque capital
- Lake City - tobacco trading center - south of Florence
- Lake Marion - Santee State Park
- Lancaster - southeast of Charlotte
- Lexington - Lake Murray, boating
- Lugoff - just west of Camden
- Manning - Lake Marion, fishing - close to I-95
- Marion - east of Florence
- Newberry - Newberry College - Newberry Opera House
- North Augusta - golf
- Orangeburg - SC State University, Claflin University
- Pageland
- Richburg
- Ridgeway - north of Columbia - close to I-77
- Rock Hill - Winthrop College - south of Charlotte
- Santee - Lake Marion, fishing - close to I-95
- Summerton - Lake Marion, fishing - close to I-95
- Sumter - Shaw Air Force Base
- Turbeville - east of Sumter, close to I-95
- West Columbia - airport
- Winnsboro - SC Railroad Museum
- York - Historic Brattonsville
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